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A Systematic Review on Thread Embedding Therapy of Knee Osteoarthritis
퇴행성 슬관절염의 매선 치료에 대한 체계적 문헌 고찰
Korean J Acupunct 2018;35:159-165
Published online December 27, 2018;
© 2018 Society for Meridian and Acupoint.

Jang Mi Park1 , Jae Sung Lee1 , Eun Yong Lee1 , Jeong Du Roh2 , Na Young Jo2 , Cham Kyul Lee1
박장미1, 이재성1, 이은용1, 노정두2, 조나영2, 이참결1

1Department of Acupuncture & Moxibustion Medicine, Semyung University Chungju Hospital of Korean Medicine, 2Department of Acupuncture & Moxibustion Medicine, Semyung University Jecheon Hospital of Korean Medicine
1세명대학교 충주한방병원 침구과, 2세명대학교 제천한병병원 침구과
Correspondence to: Cham Kyul Lee
Department of Acupuncture & Moxibustion Medicine, Semyung University Chungju Hospital of Korean Medicine, 63 Sangbang 4-gil, Cheogju 27429, Korea
Tel: +82-43-841-1738, Fax: +82-43-856-1731, E-mail:
Received November 2, 2018; Revised November 22, 2018; Accepted November 23, 2018.
This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objectives : This study was performed to review the efficacy of national and international randomized controlled trials (RCTs) investigating evidence on thread embedding therapy for knee osteoarthritis.
Methods : Online databases (PubMed, EMBASE, Cochrane, NDSL, OASIS, CNKI) were searched for studies where thread embedding therapy was performed for Knee Osteoarthritis from their inception to July 2018. Two researchers independently performed the search. Only RCTs were selected. Eligible studies were selected first by the abstract and the title and then included after full-texts were read. Risk of bias of the included studies were evaluated using the Cochrane risk of bias assessment tool. Data were narratively summarized. 
Results : There were 334 studies retrieved from the databases, resulting in analysis of 3 RCTs. There was an average of 1.5 treatment visits over a 7 day period and evaluation tool used was efficacy rate, with traditional acupuncture being the most common control used in the trials. Statistically significant improvement by thread embedding therapy was reported. None of the included RCTs reported on adverse reactions. The risk of bias of the included studies was generally unclear.
Conclusion : The review suggests that thread embedding therapy can be effective in knee osteoarthritis. But there was a lack of detailed information about the treatment procedures, and the risk of bias was unclear. Therefore, there is insufficient evidence for thread embedding therapy for knee osteoarthritis.
Keywords: knee osteoarthritis, thread embedding, randomized controlled trials, systematic review

December 2018, 35 (4)
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