Data of included studies
First author (year) | Outcome measurement | Treatment | Main result (IG/CG) | |
---|---|---|---|---|
1.Lin (2016)17) | 1. TER | IG | CA+MR (+NKT) (CA=董氏奇穴) | 1. 98% (49/50)/77.8% (35/45) ( |
CG | WM | |||
2.Deng (2016)18) | 1. TER | IG | NKT+HM | 1. 90% (27/30)/70% (21/30) ( |
CG | CA | |||
3.Hong (2017)19) | 1. TER | IG | NKT+CA(CA=太极六合针) | 1. 86.7% (26/30)/60% (18/30) ( |
CG | CA | |||
4.Yang (2017)20) | 1. TER | IG | NKT | 1. 89% (89/100)/77% (77/100) ( |
CG | CA | |||
5.Liang (2019)21) | 1. TER 2. VAS 3. SAS 4. SDS |
IG | NKT | 1. 9,286.55% (28/29)/68.97% (20/29) ( 2. 7.42±0.59→1.02±0.37/7.39±0.47→3.58±0.25 ( 3. 72.63±4.52→10.15±0.29/71.94±5.26→21.45±0.38 ( 4. 71.89±5.03→13.68±0.41/70.96±4.22→22.57±0.24 ( |
CG | EA | |||
6.Ma (2020)22) | 1. TER | IG | NKT | 1. 98% (39/40)/88% (35/40) ( |
CG | EA | |||
7.Fu (2021)23) | 1. TER 2. VAS 3. HIT-6 |
IG | NKT | 1. 83.3% (65/78)/57.7% (41/71) ( 2. 7.95±1.66→3.52±1.68 (BT>AT: 3. 60.25±5.74→45.21±5.44 (BT>AT: |
CG | EA | |||
8.Zhu (2021)24) | 1. TER 2. VAS 3. SI |
IG | NKT+HM | 1. 96.67% (29/30)/73.33% (22/30) ( 2. 8.08±0.81→3.13±1.58 (BT>AT: 3. ① IL-6: 7.98±2.00→3.17±1.61 (BT>AT: ② hs-CRP: 5.55±2.08→1.65±1.10 (BT>AT: |
CG | WM | |||
9.Wang (2022)25) | 1. TER 2. VAS 3. TSS 4. SI |
IG | NKT | 1. 96.08% (49/51)/84.31% (43/51) ( 2. 6.37±1.84 (BT)→3.51±1.06 (1 wk AT)→2.07±0.54 (2 wks AT)→0.89±0.07 (3 wks AT)/6.05±1.77 (BT)→4.52±1.23 (1 wk AT)→3.41±1.12 (2 wks AT)→1.95±0.85 (3 wks AT) (BT: 3. ① Headache (头痛): 4.28±1.03→1.87±0.61/4.09±0.98→2.95±0.75 ② Irritability (心烦易怒): 3.58±1.12→1.02±0.35/3.24±1.07→2.54±0.68 ③ Red eyes (目赤): 4.15±1.21→1.23±0.25/3.96±1.13→1.97±0.53 ④ Bitter mouth (口苦): 2.77±0.51→1.22±0.16/2.65±0.48→2.03±0.31 (BT: 4. ① MMP-9: 118.29±10.53→80.54±8.22/117.94±10.27→89.71±9.03 ② 5-HT: 72.35±10.51→97.66±15.46/71.79±10.42→91.34±14.57 ③ NOS: 73.02±2.55→53.48±2.63/72.89±2.14→62.17±2.79 (BT: |
CG | CA | |||
10.Feng (2023)26) | 1. TER 2. VAS 3. HSS 4. HIT-6 |
IG | NKT | 1. ① 1 month AT: 93.94% (31/33)/87.10% (27/31) ② 3 months AT: 87.88% (29/33)/77.42% (24/31) 2. 7.00* (BT)→3.00* (1 month AT)→4.00* (3 months AT)/7.00* (BT)→4.00* (1 month AT)→5.00* (3 months AT)(BT>AT: 3. ① BT: no statistically significant difference in the each item of headache score and total scores between the two groups ( ② 1 month, 3 months AT: each item of the headache score and the total score for both groups were significantly lower than BT ( ③ The lower range: IG>CG (except for comorbidities and other symptoms) ( 4. ① BT: no statistically significant difference in the each item of headache score and total scores between the two groups ( ② 1 month, 3 months AT: each item of the headache score and the total score for both groups were significantly lower than BT ( ③ The lower range: IG>CG ( |
CG | WM |
CA : common acupuncture (=毫鍼), MR : manipulative reduction, NKT : needle knife therapy (=acupotomy), WM : western medicine, HM : herbal medicine, EA : electro-acupuncture, TER : total efficacy rate, VAS : visual analogue scale, SAS : self-rating anxiety scale, SDS : self-rating depression scale, HIT-6 : headache impact test-6, BT : before treatment, AT : after treatment, SI : serological indicators, IL : interleukin, hs-CRP : high sensitivity-C reactive protein, TSS : traditional Chinese medicine symptom score, wk(s) : week(s), HSS : headache scale score, MP : metalloproteinases, HT : hydroxytryptamine, NOS : nitric oxide synthase,