Korean Journal of Acupuncture

Table. 2.

Table. 2.

Acupuncture effects on wrinkles in the randomized controlled trials

Author
(year)
N Therapeutic technique Treatment area Result

Experimental Control
Acupuncture+Routine care vs. Routine care
Park (2012)9) 30 MTS&High frequency+ C ample+C mask+C ample&Sun cream C ample+C mask+ C ample&Sun cream - [Exp] WL) HF: −10%, MTS: −29%, PI) HF: 0%, MTS: −19%, Pole) HF:−2%, MTS:−15%
[Con] WL: +2%, PI: +1%, Pole: +0%
Zasada (2019)16) 17 MTS+L-ascrobic Serum L-ascrobic Serum Cheek, fore head [Exp] Cheek) EL: +14%, HY: +10%, M: −11%, SF: +50%, Forehead) EL: +49%, HY: +10%, M: −9%, SF: +42%
[Con] Cheek) EL: +11%, HY: +15%, M: −14%, SF: +10%, Forehead) EL: +8%, HY: +12%, M: −10%, SF: +10%
Park (2017)17) 34 MTS+HA polymer Whitening essence - [Exp] M: −9%, SB: 1.2%
[Con] M: −5%, SB: 0.6%
Nam (2016)14) 25 MTS+HA Untreated Lower cheek [Exp vs. Con] HY: 142%, M:−14%, EL: 335%
Kang (2018)21) 22 MTS+Adenosine Adenosine cream Crow’s feet [Exp] WD: −4.4%, DD: +0.7%, EL: +1.5%, HY: +2.8%
[Con] WD: −4%, DD: +0.2%, EL: +1.3%, HY: +2%
Acupuncture+Routine care vs. Acupuncture
Kim (2015)36) 45 MTS+4-n- butylresorcinol MTS Face [Exp] M: −7%, ITA value: +6%
[Con] M: −3%, ITA value: +3%
Hong (2018)22) 84 MTS+HA+Adenosine wrinkle cream 1) MTS+HA
2) Adenosine wrinkle cream
CF, NF [Exp] CF: −34%, NF: −25%, EL: +16%
[Con 1] CF: −27%, NF: −42%, EL: +14%
[Con 2] CF: −8%, NF: −80%, EL: +12%
Lee (2014)23) 35 MTS+EGF ample MTS - [Exp] W: −27%, EL: +75%, HY: +95%, PI: −22%
[Con] W: −12%, EL: +35%, HY: +39%, PI: −16%
Lee (2014)34) 25 MTS+EPC MTS Face [Exp] M: −19%, SR: −23%
[Con] M: −5%, SR: −12%
Lee (2016)47) 23 MTS+HA (right side) MTS (left side) Crow’s feet [Exp] GPS: −11%
[Con] GPS: 0%

Outcome values are expressed as a percentage of a decrease or increase after treatment compared to before treatment. Outcome values of Nam (2016)14) are expressed as a percentage of a decrease or increase after treatment compared to the control. Outcome values of Kang (2018)21) was the data measured 8 weeks after treatment. C : Colagen, CF : Crow’s feet wrinkle, Con : Control group, DD : Dermal density, EL : Elasticity, EPC : Endothelial precursor cell, Exp : Experimental group, GPS : Global photodamage score, HA : Hyaluronic acid, HF : High frequency, HY : Hydration, IO : Infra orbital wrinkle, ITA : Individual typology angle, M : Melanin, MTS : Microneedle therapy system, N : Number of patient, NF : Nasolabial fold wrinkle, NL : Nasolabial wrinkle, PI : Pigmentation, SB : Skin brightness, SF : Skin firmness, SR : Skin roughness, W : Wrinkle, WD : Wrinkle depth, WL : Wrinkle length, - : Not reported.

Korean J Acupunct 2021;38:62-74 https://doi.org/10.14406/acu.2021.009
© 2021 Korean J Acupunct