Korean Journal of Acupuncture

Table. 6.

Table. 6.

Historical control data

Historical control values of micro nucleated polychromatic erythrocytes (MNPCE)

GroupHours after dosing (hr)Dose (ml/kg)NMNPCE/PCE (%) (Mean±S.D.)Range [MNPCE/PCE] (%)

Negative control2401850.03±0.0300.11*
Positive control2421855.87±1.451.51*10.23*

Historical control values of ratio of polychromatic erythrocytes (PCE) to total erythrocytes

GroupHours after dosing (hr)Dose (ml/kg)NPCE/(NCE+PCE) (%) (Mean±S.D.)Range [PCE/ (NCE+PCE)] (%)


Negative control24018533.74±4.9218.99*48.49*
Positive control24218531.41±4.8516.85*45.98*

Negative control: Water for injection, Normal saline injection, Corn oil, 0.5% methyl cellulose 1500centipoise solution, 0.5% carboxymethylcellulose sodium salt solution, Phosphate buffered saline, etc.

N : The total number of micronucleus test.

Positive control: Mitomycin C (2 mg.kg, I.P., single dosing).

The above historical control values were obtained from the data pooled from Dec. 9, 2009 to Apr. 6, 2017.

The range was calculated by the control limit from Mean±3×S.D.

Korean J Acupunct 2019;36:74-80 https://doi.org/10.14406/acu.2019.002
© 2019 Korean J Acupunct