Korean Journal of Acupuncture

Table. 5.

Table. 5.

The ratio of polychromatic erythrocytes (PCE) to total erythrocytes in male mice in vivo micronucleus test

 GroupDose (ml/animal)Number of animalsRouteHours after dosing (hr)PCE (PCE+NCE)MNPCE/PCE
Normal saline05I.M.24Total780/2,5008/10,000
% (Mean±S.D.)31.2±40.08±0
TA0.055I.M.24Total764/2,5007/10,000
% (Mean±S.D.)30.6±60.07±0
0.15I.M.24Total865/2,50011/10,000
% (Mean±S.D.)34.6±20.11±0
0.25I.M.24Total649/2,5009/10,000
% (Mean±S.D.)26.0±40.09±0
MMC2 mg/kg5I.P.24Total698/2,500682††/10,000
% (Mean±S.D.)27.9±56.82±1

I.M. : Intramuscular, I.P. : Intraperitoneal, MNPCE : Micro nucleated polychromatic erythrocytes, PCE : Polychromatic erythrocytes, NCE : Nomochromatic erythrocytes, MMC : mitomycin C, S.D. : Standard Deviation.

Significanct difference from negative control by Kastenbaum&Bowman :

p<0.01.

Korean J Acupunct 2019;36:74-80 https://doi.org/10.14406/acu.2019.002
© 2019 Korean J Acupunct